What enzyme is used to soften the zonules of the lens before cataract surgery?

What enzyme is used to soften the zonules of the lens before cataract surgery?

• A. Atropine sulfate
• B. Alpha-chymotrypsin
• C. Acetylcholine chloride
• D. Pilocarpine hydrochloride

Answer: (B)

The enzyme that is used to soften the zonules of the lens before cataract surgery is alpha-chymotrypsin. This proteolytic enzyme acts by breaking down the protein structure of the zonules, which are the fibrous ligaments that hold the lens in place. Softening the zonules facilitates the removal of the lens during cataract surgery, allowing for easier manipulation and extraction of the cataract-affected lens. Other options are used in different contexts within ocular procedures but do not serve the same purpose. Atropine sulfate is commonly used to dilate the pupil and paralyze the ciliary muscle, thereby preventing accommodation. Acetylcholine chloride is employed to induce miosis, creating a smaller pupil for surgical procedures. Pilocarpine hydrochloride also causes miosis and is used to manage intraocular pressure but does not have the effect of softening the zonules. Thus, alpha-chymotrypsin is specifically indicated for its ability to soften the zonules effectively before cataract surgery.

The enzyme that is used to soften the zonules of the lens before cataract surgery is alpha-chymotrypsin. This proteolytic enzyme acts by breaking down the protein structure of the zonules, which are the fibrous ligaments that hold the lens in place. Softening the zonules facilitates the removal of the lens during cataract surgery, allowing for easier manipulation and extraction of the cataract-affected lens.

Other options are used in different contexts within ocular procedures but do not serve the same purpose. Atropine sulfate is commonly used to dilate the pupil and paralyze the ciliary muscle, thereby preventing accommodation. Acetylcholine chloride is employed to induce miosis, creating a smaller pupil for surgical procedures. Pilocarpine hydrochloride also causes miosis and is used to manage intraocular pressure but does not have the effect of softening the zonules. Thus, alpha-chymotrypsin is specifically indicated for its ability to soften the zonules effectively before cataract surgery.